Both PubMed and Embase provide basic searches when you open them. You can just enter search terms as keywords, and you do not need to use Boolean operators (e.g., AND, OR, etc.). You can build a more complex search though if you want. In PubMed the advanced search is linked under the search box. In Embase the advanced search link is in the second/lower menu bar.
PubMed's homepage offers some unique links:
In Embase, you will see some different features:
Note that if you are just running a basic search with keywords (or using Booleans) you can copy and paste your search into the other database--it will work in both!
Click on the "?" below to learn more about each database's homepage interface.